Selank 10mg

Selank is the heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro. The first four residues are tuftsin, an immunopeptide released from the Fc fragment of immunoglobulin G. The last three are Pro-Gly-Pro, the same C-terminal extension carried by Semax.

Both compounds came out of the same design programme, which took a short bioactive sequence and appended a proline-rich tail to block peptidase cleavage. Semax applied it to an ACTH fragment, Selank to tuftsin. Running the two together isolates what the parent sequence contributes from what the stabilising tail contributes.

Published work has examined GABAergic signalling, inhibition of enkephalin-degrading enzymes, which extends the lifetime of endogenous enkephalins, and modulation of interleukin-6 and interferon expression. The immune arm traces back to the tuftsin origin: the parent peptide is a phagocytosis stimulant, not a neuropeptide, and Selank carries measurable activity on both sides.

Rodent models have measured anxiety-related behaviour, learning, and cytokine response.

Supplied as a lyophilised powder at ≥99% purity by HPLC, with batch LC-MS identity confirmation and a certificate of analysis. Reconstitute with bacteriostatic water. Store the sealed vial at -20°C and keep reconstituted solution at 2-8°C, protected from light.

For in-vitro laboratory research only. Not for human or veterinary use.